HUMBOLDT HARVEST
Medical Cannabis Formulary
Dual Licensed
Method No. 01 · Cryogenic Hydrocarbon Extraction

The full plant,
extracted in the cold.

Humboldt Harvest is a specialized hydrocarbon processor running at cryogenic temperatures. We preserve the complete cannabinoid and terpene fingerprint of a single cannabis strain — never re-blended, never reconstructed, formulated for medical applications.

THCa · 105°
CBG · 52°
CBDa · 120°
THCV · 93°
Skeletal · Cannabinoid base
Process
Hydrocarbon, Cryogenic
Spectrum
Full Plant, Single Strain
Origin
Humboldt County, CA
License
CDPH Type 7 · Medical
cryogenic · cryogenic · cryogenic · cryogenic · cryogenic · cryogenic · cryogenic · cryogenic · 
Cryogenic Hydrocarbon −40°C Process Single Strain, Single Pour Full Spectrum Retained Third-Party Lab Validated Arcata, California CDPH Type 7 Manufacturer DEA Application Filed Cryogenic Hydrocarbon −40°C Process Single Strain, Single Pour Full Spectrum Retained Third-Party Lab Validated Arcata, California CDPH Type 7 Manufacturer DEA Application Filed
Specifications, in motion

Discipline, by the numbers.

−0°C
Operating Temperature
0+
Compounds Preserved per Batch
0%
Solvent-Purity Floor
0
Strain · Single-Pour Discipline
Live Signal · Sample Run

What the spectrum looks like.

Chromatogram from a representative cryogenic-process lot. Each peak corresponds to a discrete compound resolved from the resin. The full panel — over 140 cannabinoid and terpene entities — is published per batch.
Lot 0314 · Cryo-HC · −40°C Acquiring
THCa
2.4 min
CBDa
5.1 min
CBG
7.8 min
CBN
10.3 min
CBC
12.7 min
α-Pinene
1.1 min
RT retention time
AU absorbance units
λ 220 nm
N 142 entities
A single discipline
precision precision precision

Three letters off in temperature is the difference between a complete spectrum and a damaged one. We choose to be precise.

The Process

A closed loop. Below freezing. Strain by strain.

001 · INPUT
01 · Biomass

Single strain. Single harvest.

Inputs are kept strain-pure from receiving through staging. No blending across cultivars, no aggregated lots, no provenance ambiguity.

−40° 002 · COLD
02 · Cryogenic Extraction

Closed-loop, below freezing.

The solvent is brought to cryogenic temperatures before contact with the biomass. The cold preserves volatile mono-terpenes and acidic cannabinoids that warmer processes drive off.

SPECTRUM LOT 0314 003 · OUTPUT
03 · Validation

Lot-by-lot chemistry.

Every batch is third-party analyzed for full cannabinoid and terpene panel, residual solvents, and contaminants. The chromatogram is published as part of the product record.

Why the Cold Matters

What survives, and at what temperature.

Each compound in cannabis has a boiling point — the temperature at which it transitions from preserved to lost. Most extraction methods operate well above several of these thresholds. Cryogenic extraction operates below all of them.

−50°C0°C100°C200°C250°C
Cryogenic Process
−40°C OPERATING
Cold Ethanol
−20°C
Standard CO₂
60°C
Short-Path Distillation
180°C
Preserved at <52°C
CBG · 52°THCV · 93°Humulene · 107° THCa · 105°CBDa · 120°Pinene · 155° Caryophyllene · 160°Myrcene · 167°Limonene · 176° CBN · 185°Linalool · 198°CBC · 220°

Boiling points sourced from peer-reviewed cannabis chemistry literature. Process temperatures are representative ranges, not specific to any operator. All values approximate.

Compound Spectrum

Six compounds the cold makes possible.

Illustrative profile of compounds preserved at cryogenic temperatures. Final concentrations vary by strain and harvest.
THCa
Tetrahydrocannabinolic acid

Acidic precursor to THC. Non-intoxicating in its native form. Retained at cryogenic temperatures; converts above 105°C.

Volatility
> 105°C
Therapeutic Interest
Anti-inflammatory · Neuroprotective
CBDa
Cannabidiolic acid

The carboxylated form of CBD. Higher receptor affinity than its neutral counterpart in some pathways. Lost above 120°C.

Volatility
> 120°C
Therapeutic Interest
Anti-nausea · Anti-inflammatory
CBG
Cannabigerol

Often called the "stem cell" cannabinoid — biosynthetic precursor to most others. Easily lost to heat.

Volatility
> 52°C
Therapeutic Interest
Antibacterial · Neuroprotective
CBN
Cannabinol

Oxidative degradation product of THC, with its own distinct receptor profile. Sensitive to extraction temperatures.

Volatility
> 185°C
Therapeutic Interest
Sedative · Anti-convulsant
CBC
Cannabichromene

Non-intoxicating, increasingly studied for anti-inflammatory and analgesic activity. Retained at low temperatures.

Volatility
> 220°C
Therapeutic Interest
Analgesic · Anti-inflammatory
THCV
Tetrahydrocannabivarin

Structurally similar to THC but with a shorter side chain — and a meaningfully different therapeutic profile.

Volatility
> 93°C
Therapeutic Interest
Appetite-suppressing · Anti-convulsant
Terpene Fingerprint

The volatile half of the plant.

Terpenes are the most fragile compounds in cannabis. They evaporate first, oxidize easily, and disappear in any process that touches them with heat. They are also the molecules clinical literature increasingly associates with the therapeutic differences between strains.

Myrcene
Herbaceous, musky
167°C
Pinene
Resinous, pine
155°C
Limonene
Citrus, bright
176°C
Linalool
Floral, soft
198°C
Caryophyllene
Pepper, woody
160°C
Humulene
Earthy, hops
107°C
A note on intention
"We are not in the recreation business. We are not in the lifestyle business. We are in the business of preserving what the plant made, and putting it in the hands of clinicians who already prescribe it."
Humboldt Harvest
Regulatory Position

Dual-licensed manufacturer.

State · Active

California

CDPH Type 7 Manufacturer license with the medical endorsement required to apply for federal pathway. Operating from a permitted facility in Arcata, California.

License Class
CDPH Type 7
Medical Endorsement
Active
Issuing Authority
CDPH / DCC
Status
In Good Standing
Federal · Application Filed

DEA Pathway

Federal manufacturer registration application filed via the DEA portal. Operations continue under existing state authority while the agency completes its determination.

Application
Filed
Review Window
60 Days
Operational Posture
Continuing
Final Scope
Pending Determination
Regulatory Notice

Humboldt Harvest does not make therapeutic claims for the diagnosis, treatment, cure, or prevention of any disease. Products are intended for patients whose clinicians have independently determined cannabis to be appropriate for their care. All materials are for licensed-clinician and qualified-patient audiences.